abstract：:A proangiogenic micromilieu is associated with a worse prognosis in systemic lymphoma. Hence, targeting the tumour microenvironment and its vasculature has evolved as a promising novel treatment strategy. The role of tumour neoangiogenesis in cutaneous B-cell lymphoma, however, has not yet been elucidated. Therefore, ...

journal_title：Acta dermato-venereologica

authors： Wobser M,Siedel C,Kneitz H,Bröcker EB,Goebeler M,Houben R,Geissinger E

更新日期：2013-11-01 00:00:00

abstract：:Many patients with psoriasis demonstrate psychological disturbances, including decreased health-related quality of life (HRQoL). The aim of this study was to evaluate selected personal resources and HRQoL in 168 in-patients with psoriasis vulgaris. The following questionnaires were used: Skindex-29, General Health Que...

journal_title：Acta dermato-venereologica

authors： Miniszewska J,Juczyński Z,Ograczyk A,Zalewska A

更新日期：2013-09-04 00:00:00

abstract：:Biological drugs are expensive, but can reduce symptoms and increase quality of life for patients with psoriasis. The aim of this study was to examine quality of life, disease severity and treatment satisfaction in Danish, Finnish and Swedish patients with psoriasis. Based on 12 months' data from patient surveys and c...

journal_title：Acta dermato-venereologica

authors： Ragnarson Tennvall G,Hjortsberg C,Bjarnason A,Gniadecki R,Heikkilä H,Jemec GB,Kragballe K,Miller IM,Svensson Å

更新日期：2013-07-06 00:00:00

abstract：:Non-melanoma skin cancer (NMSC) is the most frequent malignancy in organ transplant recipients. The aetiology of NMSC after transplant is multifactorial. The aim of this study was to determine the clinical and environmental factors involved in the development of NMSC in a Spanish kidney transplant population from the ...

journal_title：Acta dermato-venereologica

authors： Bernat García J,Morales Suárez-Varela M,Vilata JJ,Marquina A,Pallardó L,Crespo J

更新日期：2013-07-06 00:00:00

abstract：:We conducted a retrospective study of patients with cutaneous myeloid sarcoma, from 2 tertiary care institutions. Eighty-three patients presented, with a mean age of 52 years. Diagnosis of myeloid sarcoma in the skin was difficult due to the low frequency of myeloperoxidase and/or CD34+ cases (56% and 19% of tested ca...

journal_title：Acta dermato-venereologica

authors： Hurley MY,Ghahramani GK,Frisch S,Armbrecht ES,Lind AC,Nguyen TT,Hassan A,Kreisel FH,Frater JL

更新日期：2013-05-01 00:00:00

abstract：:Pain and discomfort are common and often severe skin symptoms in patients with psoriasis. However, no studies have investigated skin pain and discomfort over time, or factors that explain changes in these symptoms. The aims of the present study were to describe the changes in skin pain, skin discomfort and Psoriasis A...

journal_title：Acta dermato-venereologica

authors： Ljosaa TM,Stubhaug A,Mork C,Moum T,Wahl AK

更新日期：2013-05-01 00:00:00

abstract：:The recovery of skin function and appearance after harvest of split-thickness skin autografts is incompletely described. We followed the kinetics of skin restoration after a partial-thickness skin excision relative to adjacent normal skin over 12 months. Standardized donor site wounds were made on the thigh using a pn...

journal_title：Acta dermato-venereologica

authors： Danielsen PL,Jorgensen LN,Jørgensen B,Karlsmark T,Agren MS

更新日期：2013-05-01 00:00:00

abstract：:High-dose intravenous immunoglobulin (IVIG) therapy is used in patients with severe autoimmune blistering diseases that are refractory to standard immunosuppressive therapy. To determine the efficacy and frequency of adverse events of IVIG therapy, we retrospectively analysed data for 16 patients with pemphigus vulgar...

journal_title：Acta dermato-venereologica

authors： Seidling V,Hoffmann JH,Enk AH,Hadaschik EN

更新日期：2013-05-01 00:00:00

abstract：:The aim of this study is to assess the associations between chronic spontaneous urticaria (CSU), Helicobacter pylori infection and small intestinal bacterial overgrowth. Forty- eight patients with CSU were studied by scoring the urticaria activity and assesing the quality of life. Patients with H. pylori infection (n=...

journal_title：Acta dermato-venereologica

authors： Campanati A,Gesuita R,Giannoni M,Piraccini F,Sandroni L,Martina E,Conocchiari L,Bendia E,Di Sario A,Offidani A

更新日期：2013-03-27 00:00:00

abstract：:Gestational pemphigoid (PG), a very rare pregnancy-associated bullous dermatosis, is associated with adverse pregnancy outcome (miscarriage, preterm delivery, foetal growth restriction). The major antigen in PG is collagen XVII (BP180). PG autoantibodies cross-react with collagen XVII in the skin and have been suggest...

journal_title：Acta dermato-venereologica

authors： Huilaja L,Mäkikallio K,Sormunen R,Lohi J,Hurskainen T,Tasanen K

更新日期：2013-01-01 00:00:00

abstract：:Regulatory T cells (Tregs), identified by the expression of CD4, CD25 and Foxp3, together with immunosuppressive macrophages, such as CD163+ M2 macrophages, are involved in maintaining peripheral tolerance. The aim of this study was to elucidate the involvement of Tregs and CD163+ macrophages in invasive and non-invas...

journal_title：Acta dermato-venereologica

authors： Fujimura T,Kambayashi Y,Hidaka T,Hashimoto A,Haga T,Aiba S

更新日期：2012-11-01 00:00:00

abstract：:It has been shown recently that immunotherapy for advanced melanoma is effective. However, in order to improve the efficacy of immunotherapy, the identification of more specific melanoma-associated antigens is urgently needed. Kinesin family member 20A (KIF20A) has been reported to be a promising immunotherapeutic tar...

journal_title：Acta dermato-venereologica

authors： Yamashita J,Fukushima S,Jinnin M,Honda N,Makino K,Sakai K,Masuguchi S,Inoue Y,Ihn H

更新日期：2012-11-01 00:00:00

abstract：:An observational, questionnaire-based, cross-sectional study was performed to assess whether differences in coping behaviour (positive and negative strategies) between patients with either a recent diagnosis of malignant melanoma (MM) or with benign dermatological disease, were predictive of the diagnosis. Coping stra...

journal_title：Acta dermato-venereologica

authors： Trapp M,Trapp EM,Richtig E,Egger JW,Zampetti A,Sampogna F,Rohrer PM,Komericki P,Strimitzer T,Linder MD

更新日期：2012-11-01 00:00:00

abstract：:Itch is the most common dermatological symptom and worsens with stress. The general belief of a person in their own ability to cope in stressful situations, known as self-efficacy, is relevant in the management of chronic diseases other than skin diseases. The aim of this study was to explore the association between p...

journal_title：Acta dermato-venereologica

authors： Dalgard F,Stern R,Lien L,Hauser S

更新日期：2012-09-01 00:00:00

abstract：:The association between itch and suicidal ideation has not been explored previously in the general population. The aim of the present study is to analyse the association between itch and suicidal ideation in adolescents, and to compare the findings with an expected association between pain and suicidal ideation in the...

journal_title：Acta dermato-venereologica

authors： Halvorsen JA,Dalgard F,Thoresen M,Bjertness E,Lien L

更新日期：2012-09-01 00:00:00

abstract：:Dapsone is widely used in the treatment of leprosy and several chronic inflammatory dermatological conditions. Hypersensitivity reactions to dapsone are potentially fatal adverse drug reactions with unknown prevalence and risk factors. We performed a systematic review covering all reported cases of hypersensitivity re...

journal_title：Acta dermato-venereologica

authors： Lorenz M,Wozel G,Schmitt J

更新日期：2012-03-01 00:00:00

abstract：:Diagnosing gonorrhoea from extra-genital as well as genital sites is important in managing this sexually transmitted disease. In this study we evaluated a screening procedure for Neisseria gonorrhoeae (GC) from all sample sites in a low-prevalence setting. A total of 69,252 specimens submitted for Chlamydia trachomati...

journal_title：Acta dermato-venereologica

authors： Skovgaard S,Larsen HK,Sand C,Friis-Møller A,Schønning K,Jensen JS,Westh H

更新日期：2012-01-01 00:00:00

abstract：:Patients with psoriasis who are being treated with biologics require intensive monitoring. However, the monitoring tool teledermatology is not commonly used. We investigated the applicability of a mobile phone based teledermatological system for monitoring psoriasis patients on biologic therapy. Nineteen patients were...

journal_title：Acta dermato-venereologica

authors： Koller S,Hofmann-Wellenhof R,Hayn D,Weger W,Kastner P,Schreier G,Salmhofer W

更新日期：2011-10-01 00:00:00

abstract：:Mohs micrographic surgery allows for complete microscopic examination of the surgical margin when treating aggressive and recurrent facial basal cell carcinomas. This leads to the highest cure rates and maximal preservation of healthy tissue. The 5-year recurrence rates of 587 aggressive and/or recurrent facial basal ...

journal_title：Acta dermato-venereologica

authors： Paoli J,Daryoni S,Wennberg AM,Mölne L,Gillstedt M,Miocic M,Stenquist B

更新日期：2011-10-01 00:00:00

abstract：:We describe here 4 patients with Sézary syndrome masquerading as adult-onset atopic dermatitis. The patients presented with a clinical picture compatible with wide-spread atopic dermatitis and did not fulfil the criteria for Sézary syndrome (lack of lymphoadenopathy and blood involvement, skin histology without presen...

journal_title：Acta dermato-venereologica

authors： Sokołowska-Wojdyło M,Barańska-Rybak W,Cegielska A,Trzeciak M,Lugowska-Umer H,Gniadecki R

更新日期：2011-09-01 00:00:00

abstract：:The defined, serum-free media used in the cultivation of skin equivalents are liable to inter-laboratory variations, require the preparation of multiple additives, and are potentially difficult to replicate. In this study, we assessed the use of standardized, serum-free and bovine pituitary extract-free keratinocyte c...

journal_title：Acta dermato-venereologica

authors： Ng W,Ikeda S

更新日期：2011-06-01 00:00:00

abstract：:Autosomal dominant and recessive forms of dystrophic epidermolysis bullosa (DEB) result from mutations in the type VII collagen gene (COL7A1). Although paradigms have emerged for genotype/phenotype correlation in DEB, some pathogenic mutations in COL7A1, notably glycine substitutions within the type VII collagen tripl...

journal_title：Acta dermato-venereologica

authors： Almaani N,Liu L,Dopping-Hepenstal PJ,Lai-Cheong JE,Wong A,Nanda A,Moss C,Martinéz AE,Mellerio JE,McGrath JA

更新日期：2011-05-01 00:00:00

abstract：:p38 mitogen-activated protein kinase plays a pivotal role in skin inflammation. The purpose of this study was to investigate the role of the various p38 isoforms. p38β/δ-knockout-C57BL/6 mice were generated, studied in a 12-O-tetradecanoylphorbol 13-acetate (TPA)-induced skin inflammation model and compared with wild-...

journal_title：Acta dermato-venereologica

authors： Lilleholt LL,Johansen C,Arthur JS,Funding A,Bibby BM,Kragballe K,Iversen L

更新日期：2011-05-01 00:00:00

abstract：:Multicentric reticulohistiocytosis is a rare systemic disease of unknown aetiology characterized by erosive arthritis and cutaneous lesions consisting of multiple reddish-brown papules and nodules, mainly involving the face and distal upper extremities. It has been suggested that skin eruptions in multicentric reticul...

journal_title：Acta dermato-venereologica

authors： Taniguchi T,Asano Y,Okada A,Sugaya M,Sato S

更新日期：2011-03-01 00:00:00

abstract：:Atopic dermatitis (AD) has a big impact on quality of life. The usefulness of health-related quality of life questionnaires for children with AD in general practice, and the relationship of quality of life to disease severity, as assessed by parents and by investigators, however, is not known. This study used the Infa...

journal_title：Acta dermato-venereologica

authors： van Valburg RW,Willemsen MG,Dirven-Meijer PC,Oranje AP,van der Wouden JC,Moed H

更新日期：2011-03-01 00:00:00

abstract：:It is well known that the genital skin may be affected by psoriasis. However, little is known about the prevalence and clinical appearance of genital psoriasis, and genital skin is often neglected in the treatment of psoriatic patients. We performed an extensive systematic literature search for evidence-based data on ...

journal_title：Acta dermato-venereologica

authors： Meeuwis KA,de Hullu JA,Massuger LF,van de Kerkhof PC,van Rossum MM

更新日期：2011-01-01 00:00:00

abstract：:Psychological stress and atopic dermatitis (AD) symptoms appear to form a vicious cycle. This study compared the degree of stress and impairment of dermatology life quality between patients with AD and healthy controls, and examined for neuropeptides and neurotrophins associated with stress in AD. Questionnaires, comp...

journal_title：Acta dermato-venereologica

authors： Oh SH,Bae BG,Park CO,Noh JY,Park IH,Wu WH,Lee KH

更新日期：2010-11-01 00:00:00

abstract：:In order to explore the mechanisms of inflammatory skin disorders, we established two methods of expanding skin-derived lymphocytes, one using high levels of interleukin (IL)-2 and IL-4 (method A) and the other using low levels of cytokines and anti-CD3/CD28 microbeads (method B). Both methods provide advantages for f...

journal_title：Acta dermato-venereologica

authors： Hashizume H,Hansen A,Poulsen LK,Thomsen AR,Takigawa M,Thestrup-Pedersen K

更新日期：2010-09-01 00:00:00

abstract：:Confounding from comorbidity and socioeconomic status may have biased earlier findings of all-cause mortality among patients with basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). We therefore examined all-cause mortality among 72,295 Danish patients with BCC, 11,601 with SCC, and 383,714 age- and gender-m...

journal_title：Acta dermato-venereologica

authors： Jensen AØ,Lamberg AL,Jacobsen JB,Braae Olesen A,Sørensen HT

更新日期：2010-07-01 00:00:00

abstract：:A skin biopsy is one of the most frequently performed procedures in the dermatology outpatient clinic, but doctors often do not consider the cognitive impact of the biopsy procedure. Based on "terror management theory," we reasoned that a skin biopsy increases patient compliance by unconsciously stimulating mortality ...

journal_title：Acta dermato-venereologica

authors： Kim JH,Kim J,Jung YH,Yi Y,Ahn HH

更新日期：2010-05-01 00:00:00

abstract：:Recessive dystrophic epidermolysis bullosa (RDEB) is an inherited skin disorder caused by mutations in the COL7A1 gene, which encodes collagen VII (COL7). Skin ulcers in RDEB patients are sometimes slow to heal. We describe here the therapeutic response of intractable skin ulcers in two patients with generalized RDEB ...

journal_title：Acta dermato-venereologica

authors： Natsuga K,Sawamura D,Goto M,Homma E,Goto-Ohguchi Y,Aoyagi S,Akiyama M,Kuroyanagi Y,Shimizu H

更新日期：2010-03-01 00:00:00

abstract：:Eosinophilic pustular folliculitis is an inflammatory skin disease characterized by pruritic follicular papulopustules. It is usually resistant to topical and/or systemic corticosteroids, but it responds well to systemic indomethacin. We report here two patients with classical-type disease who were treated with system...

journal_title：Acta dermato-venereologica

authors： Satoh T,Shimura C,Miyagishi C,Yokozeki H

更新日期：2010-01-01 00:00:00

abstract：:Cutaneous adverse effects of imatinib mesylate (Glivec) are common and various types of skin eruptions have been reported. We report here a 57-year-old man who presented with lichen planus-like lesions on his extremities and palmoplantar hyperkeratosis due to the use of imatinib mesylate for chronic myeloid leukaemia....

journal_title：Acta dermato-venereologica

authors： Kuraishi N,Nagai Y,Hasegawa M,Ishikawa O

更新日期：2010-01-01 00:00:00

abstract：:Hidradenitis suppurativa (HS) is a recurrent, debilitating suppurative skin disease. Nowadays the major challenge is the choice of optimal treatment. Many conservative therapies seem to have only a supportive character and do not prevent progression of the disease. Early surgical intervention with complete excision of...

journal_title：Acta dermato-venereologica

authors： Matusiak L,Bieniek A,Szepietowski JC

更新日期：2009-11-01 00:00:00

abstract：:Itch is known to be associated with psychological factors in adults, but has not been explored among adolescents. A cross-sectional, questionnaire-based population study involving adolescents born mostly in 1986 was carried out in 2004. A total of 4744 individuals were invited and the participation rate was 80%. The H...

journal_title：Acta dermato-venereologica

authors： Halvorsen JA,Dalgard F,Thoresen M,Thoresen M,Bjertness E,Lien L

更新日期：2009-01-01 00:00:00

abstract：:Immunotherapy with wasp allergen leads to a variety of specific immunological changes. It is unknown, however, whether unspecific effects also occur, and which parameter shifts might indicate treatment success. Therefore, data of patients who had completed immunotherapy with wasp venom were analysed retrospectively fo...

journal_title：Acta dermato-venereologica

authors： Brasch J,Maidusch T

更新日期：2009-01-01 00:00:00

abstract：:Although pruritus is an essential symptom of atopic dermatitis, its complex pathomechanism is not fully understood. The aim of this study was to characterize the clinical pattern of itch in adult subjects with atopic dermatitis. A total of 89 patients (59 females, 30 males) with atopic dermatitis, age range 18-60 year...

journal_title：Acta dermato-venereologica

authors： Chrostowska-Plak D,Salomon J,Reich A,Szepietowski JC

更新日期：2009-01-01 00:00:00

abstract：:Itching is the most frequent symptom in dermatology. Little is known about its occurrence and its characteristics in the general population. Instruments specifically designed to measure itch are scarce. The aim of this pilot study was to develop and validate an instrument measuring prevalence and characteristics of ch...

journal_title：Acta dermato-venereologica

authors： Matterne U,Strassner T,Apfelbacher CJ,Diepgen TL,Weisshaar E

更新日期：2009-01-01 00:00:00

abstract：:While localized variants of granuloma annulare are typically self-limited, disseminated granuloma annulare tends to be chronic and often therapy-resistant. Treatment with fumaric acid esters is effective for severe forms of psoriasis. Disseminated granuloma annulare has also been reported to respond to fumaric acid es...

journal_title：Acta dermato-venereologica

authors： Weber HO,Borelli C,Röcken M,Schaller M

更新日期：2009-01-01 00:00:00

abstract：:Eosinophilic pustular folliculitis is a rare dermatosis. Recently, in addition to oral indomethacin, other treatments have been applied for eosinophilic pustular folliculitis. The aim of this study was to assess the effectiveness of various therapies encompassing conventional to newly applied drugs for eosinophilic pu...

journal_title：Acta dermato-venereologica

authors： Fukamachi S,Kabashima K,Sugita K,Kobayashi M,Tokura Y

更新日期：2009-01-01 00:00:00